Nicotinamide Riboside (NR)
niagennicotinamide ribosidenr
NAD+ precursor with extensive supplementation evidence. Comparison with NMN; realistic outcomes.
- Half-life
- 1.5 h
- Out of system
- ~8 h
- Route
- Oral
- Level
- Beginner
Very short-acting — protocols dose 1–2× a day. After the last dose, roughly 97% has cleared in ~8 h (five half-lives) — the window that matters for washouts, bloodwork and surgery.
What Nicotinamide Riboside (NR) is used for
- NAD+ precursor with extensive supplementation evidence
- Reported energy and recovery support
- Oral, no injection
How it's typically used
Typical: 250–500 mg oral daily.
What to watch for
- Outcomes are often subtle
- Long-term effect on cancer pathways unclear
- Marketing claims often outrun the data
About Longevity
- What they are
- Compounds studied for cellular ageing — mitochondrial function, senescent-cell clearance, telomere and autophagy pathways.
- How they're run
- Mixed routes: some injected in short annual or biannual courses, others taken orally every day.
- What to watch
- Endpoints here are measured in decades, so nobody has human outcome data. Bloodwork and function markers are the only feedback you will get in a realistic timeframe.
Full guide
NR (Nicotinamide Riboside): Tracking a NAD+ Precursor
What NR is, how it compares to NMN, and how to track realistic outcomes from a vitamin B3 derivative marketed for cellular aging.
Other longevity
Peptid AI is an educational and self-tracking tool — not a medical service, and not a vendor. Nothing here is medical advice, a prescription, or an endorsement. Doses reflect what is commonly reported in research literature; they are not recommendations. Many compounds listed are experimental, not approved for human use, and/or controlled substances that are illegal to possess without a prescription in many countries. Always consult a qualified physician before starting, changing, or stopping any protocol.