NAD+ Direct
Direct NAD+ — IV or subcutaneous. Tracking framework weighing cost vs evidence.
- Half-life
- 30 min
- Out of system
- ~3 h
- Route
- Intravenous
- Level
- Advanced
Very short-acting — protocols dose 1–2× a day. After the last dose, roughly 97% has cleared in ~3 h (five half-lives) — the window that matters for washouts, bloodwork and surgery.
What NAD+ Direct is used for
- Direct NAD+ — IV or subcutaneous
- Reported energy and clarity in some users
How it's typically used
Research range: 100 mg subcutaneous daily, or 250 mg IV weekly.
What to watch for
- IV infusions cause intense flushing/nausea if pushed fast
- Expensive; evidence for the cost is thin
- Sterile technique essential for IV/subq
About Longevity
- What they are
- Compounds studied for cellular ageing — mitochondrial function, senescent-cell clearance, telomere and autophagy pathways.
- How they're run
- Mixed routes: some injected in short annual or biannual courses, others taken orally every day.
- What to watch
- Endpoints here are measured in decades, so nobody has human outcome data. Bloodwork and function markers are the only feedback you will get in a realistic timeframe.
Full guide
NAD+ Direct: IV, Subcutaneous, and the Question of Whether You Need Any of It
A tracking guide for direct NAD+ supplementation that takes the cost and evidence seriously.
Other longevity
Peptid AI is an educational and self-tracking tool — not a medical service, and not a vendor. Nothing here is medical advice, a prescription, or an endorsement. Doses reflect what is commonly reported in research literature; they are not recommendations. Many compounds listed are experimental, not approved for human use, and/or controlled substances that are illegal to possess without a prescription in many countries. Always consult a qualified physician before starting, changing, or stopping any protocol.