Enclomiphene
The trans-isomer of clomiphene, a selective estrogen receptor modulator (SERM) used as a testosterone-replacement alternative. It raises endogenous testosterone while preserving fertility.
- Half-life
- 1.0 d
- Out of system
- ~5 days
- Route
- Oral
- Level
- Intermediate
Daily dosing holds steady levels. After the last dose, roughly 97% has cleared in ~5 days (five half-lives) — the window that matters for washouts, bloodwork and surgery.
What Enclomiphene is used for
- Raises endogenous testosterone by stimulating the natural hormone axis
- Preserves sperm production and fertility, unlike exogenous testosterone
- Oral daily dosing with a favorable estrogen profile as the trans-isomer
How it's typically used
Literature range: 12.5-25 mg orally once daily to support endogenous testosterone, as reported in the research.
What to watch for
- Can cause visual disturbances, mood changes and headaches
- Estrogen shifts can affect lipids and require bloodwork monitoring
- Prescription SERM; use only under medical supervision
About Ancillaries (SERMs / AIs)
- What they are
- Support drugs — SERMs, aromatase inhibitors, and prolactin controls used to manage the side effects of androgen use or to restart natural production afterwards.
- How they're run
- Oral tablets, dosed against bloodwork rather than on a fixed schedule.
- What to watch
- These are only meaningful with labs in hand. Crushing oestrogen with an AI wrecks joints, libido, and lipids just as thoroughly as having too much of it.
Full guide
Enclomiphene: A Tracking Guide for a Fertility-Preserving SERM
A measured, harm-reduction look at enclomiphene, why it is used instead of exogenous testosterone, and the bloodwork that tells you whether it is working.
Other ancillaries (serms / ais)
Peptid AI is an educational and self-tracking tool — not a medical service, and not a vendor. Nothing here is medical advice, a prescription, or an endorsement. Doses reflect what is commonly reported in research literature; they are not recommendations. Many compounds listed are experimental, not approved for human use, and/or controlled substances that are illegal to possess without a prescription in many countries. Always consult a qualified physician before starting, changing, or stopping any protocol.