Tamoxifen
SERM (Nolvadex). Blocks estrogen at the breast + restarts the HPG axis in post-cycle protocols.
- Half-life
- 5.4 d
- Out of system
- ~4 weeks
- Route
- Oral
- Level
- Advanced
Long-acting — weekly dosing keeps levels steady. After the last dose, roughly 97% has cleared in ~4 weeks (five half-lives) — the window that matters for washouts, bloodwork and surgery.
What Tamoxifen is used for
- Restarts natural testosterone after a steroid cycle (post-cycle therapy)
- Blocks estrogen at breast tissue — treats/prevents gyno
- Decades of clinical use and a well-characterised safety profile
How it's typically used
PCT literature: 20 mg oral daily, tapering to 10 mg over ~4 weeks.
What to watch for
- Can raise the risk of blood clots; caution with clotting history
- Mood changes, hot flashes, and vision changes are reported
- Prescription medicine — dose and duration should be clinician-guided
About Ancillaries (SERMs / AIs)
- What they are
- Support drugs — SERMs, aromatase inhibitors, and prolactin controls used to manage the side effects of androgen use or to restart natural production afterwards.
- How they're run
- Oral tablets, dosed against bloodwork rather than on a fixed schedule.
- What to watch
- These are only meaningful with labs in hand. Crushing oestrogen with an AI wrecks joints, libido, and lipids just as thoroughly as having too much of it.
Full guide
Tamoxifen: A Tracking Guide for the SERM
A breast-cancer drug with boxed warnings, sometimes used off-label for gynecomastia or HPTA recovery. What to monitor and respect.
Other ancillaries (serms / ais)
Peptid AI is an educational and self-tracking tool — not a medical service, and not a vendor. Nothing here is medical advice, a prescription, or an endorsement. Doses reflect what is commonly reported in research literature; they are not recommendations. Many compounds listed are experimental, not approved for human use, and/or controlled substances that are illegal to possess without a prescription in many countries. Always consult a qualified physician before starting, changing, or stopping any protocol.