Melatonin
Sleep hormone. Most people take 10x too much — precision dosing improves outcomes meaningfully.
- Half-life
- 42 min
- Out of system
- ~4 h
- Route
- Oral
- Level
- Beginner
Very short-acting — protocols dose 1–2× a day. After the last dose, roughly 97% has cleared in ~4 h (five half-lives) — the window that matters for washouts, bloodwork and surgery.
What Melatonin is used for
- Strongest evidence for jet-lag and circadian phase shifting
- Lower doses (0.3–0.5 mg) work as well as 5–10 mg
- Cheap, oral, OTC
How it's typically used
Best evidence: 0.3–0.5 mg oral, 30–60 min before bed. Not 3–10 mg.
What to watch for
- Most users overdose 10× — drowsiness next day comes from too much
- Long-term high doses may affect HPG axis
- Avoid in early teens without a clinician
About Other research compounds
- What they are
- Nootropics, metabolic agents, and research compounds that don't fit the other classes.
- How they're run
- Route and schedule vary widely — check the individual entry.
- What to watch
- This is the least-characterised corner of the atlas. Read the full guide, and treat anything without published human data as exactly that.
Full guide
Melatonin: Most People Take Ten Times Too Much
A precision-dosing and sleep-tracking guide for melatonin, the most over-dosed sleep aid on the shelf.
Other other research compounds
Peptid AI is an educational and self-tracking tool — not a medical service, and not a vendor. Nothing here is medical advice, a prescription, or an endorsement. Doses reflect what is commonly reported in research literature; they are not recommendations. Many compounds listed are experimental, not approved for human use, and/or controlled substances that are illegal to possess without a prescription in many countries. Always consult a qualified physician before starting, changing, or stopping any protocol.