Skip to content

TB-500

tb500t-beta

Thymosin Beta-4 fragment — soft-tissue and tendon recovery. Long half-life relative to fragment size.

Half-life
3 h
Out of system
~15 h
Route
Subcutaneous
Level
Beginner

Short-acting — protocols usually dose daily. After the last dose, roughly 97% has cleared in ~15 h (five half-lives) — the window that matters for washouts, bloodwork and surgery.

What TB-500 is used for

  • Soft-tissue and muscle recovery (thymosin beta-4 fragment)
  • Tendon and ligament repair in animal models
  • Pairs with BPC-157 in the most-discussed recovery stack

How it's typically used

Research range: 2 mg subcutaneous twice weekly, or 5 mg weekly, for 4–6 weeks.

What to watch for

  • Long-term human safety unknown
  • Theoretical concern around abnormal cell growth pathways — avoid with cancer history
  • Not FDA-approved
  • FDA compounding status in flux: BPC-157 removed from the 503A Category 2 list (Apr 2026); PCAC review of BPC-157, TB-500, KPV and MOTS-C set for Jul 23-24, 2026.

About Healing & recovery

What they are
Repair peptides — short amino-acid chains studied for soft-tissue, tendon, and gut-lining healing. Almost all the evidence is animal or preclinical; human trials are scarce.
How they're run
Reconstituted from a lyophilised (freeze-dried) powder and injected subcutaneously, usually daily, in blocks of 4–6 weeks around a specific injury.
What to watch
None are approved drugs, so purity depends entirely on the source. Effects are gradual — judge a block by whether the injury measurably improved, not by how you feel on day 3.

Full guide

TB-500 Alone: Tracking the Thymosin Beta-4 Fragment for Recovery

A focused tracking guide for TB-500 used by itself, separating its slower recovery signal from BPC-157 and confounders.

Other healing & recovery

Peptid AI is an educational and self-tracking tool — not a medical service, and not a vendor. Nothing here is medical advice, a prescription, or an endorsement. Doses reflect what is commonly reported in research literature; they are not recommendations. Many compounds listed are experimental, not approved for human use, and/or controlled substances that are illegal to possess without a prescription in many countries. Always consult a qualified physician before starting, changing, or stopping any protocol.