Mesterolone (Proviron)
An oral DHT derivative that lowers SHBG and supports libido rather than driving large muscle gains. It is often used as an ancillary alongside other compounds.
- Half-life
- 12 h
- Out of system
- ~2.5 days
- Route
- Oral
- Level
- Intermediate
Daily dosing holds steady levels. After the last dose, roughly 97% has cleared in ~2.5 days (five half-lives) — the window that matters for washouts, bloodwork and surgery.
What Mesterolone (Proviron) is used for
- Lowers SHBG, freeing up more active testosterone in the blood
- Frequently reported to boost libido and sense of well-being
- Milder on the liver than most oral steroids
How it's typically used
Literature and anecdotal reports describe roughly 25-50 mg daily as an ancillary, framed as reported practice and not a recommendation.
What to watch for
- Weakly anabolic on its own, so it does little for muscle mass alone
- As a DHT derivative it can accelerate hair loss and prostate effects
- Can worsen cholesterol with prolonged use
- An unapproved anabolic steroid and controlled substance; illegal without a prescription in most countries
About Androgens & steroids
- What they are
- Anabolic-androgenic steroids — testosterone and its derivatives. These are drugs, not peptides, and are controlled substances in most countries.
- How they're run
- Injected intramuscularly or subcutaneously on a schedule set by the ester's half-life; a few are oral and hepatotoxic.
- What to watch
- Every one of these shuts down your own testosterone production. Full bloodwork before, during, and after is not optional, and an exit plan — PCT or ongoing replacement — is part of the decision to start, not an afterthought.
Full guide
Proviron (Mesterolone): A Tracking Guide for an Oral DHT Derivative
A measured look at mesterolone, a weakly anabolic oral DHT derivative used as an adjunct to lower SHBG and support libido, and what is worth tracking.
Other androgens & steroids
Peptid AI is an educational and self-tracking tool — not a medical service, and not a vendor. Nothing here is medical advice, a prescription, or an endorsement. Doses reflect what is commonly reported in research literature; they are not recommendations. Many compounds listed are experimental, not approved for human use, and/or controlled substances that are illegal to possess without a prescription in many countries. Always consult a qualified physician before starting, changing, or stopping any protocol.