Cardarine (GW-501516)
A PPAR-delta agonist (GW-501516) usually grouped with SARMs although it is not a true androgen modulator. It is best known for boosting endurance and fat oxidation.
- Half-life
- 1.0 d
- Out of system
- ~5 days
- Route
- Oral
- Level
- Intermediate
Daily dosing holds steady levels. After the last dose, roughly 97% has cleared in ~5 days (five half-lives) — the window that matters for washouts, bloodwork and surgery.
What Cardarine (GW-501516) is used for
- Increases endurance and fat oxidation by shifting metabolism toward fat use
- Rodent studies showed improved running capacity and lipid profiles
How it's typically used
Reported user ranges are roughly 10-20 mg daily, though no safe human dose is established.
What to watch for
- Long-term rodent studies found it caused cancer across multiple organs
- Human safety and long-term effects remain essentially unknown
- Development was abandoned; not approved for human use and banned in sport
Common questions
- What is the half-life of Cardarine (GW-501516)?
- Cardarine (GW-501516) has an approximate elimination half-life of 1.0 d. Daily dosing holds steady levels.
- How long does Cardarine (GW-501516) stay in your system?
- Roughly 97% of a dose has cleared after five half-lives — about ~5 days for Cardarine (GW-501516). That is the window that matters for washouts, bloodwork and surgery.
- How is Cardarine (GW-501516) taken?
- Cardarine (GW-501516) is typically administered by the oral route. Reported user ranges are roughly 10-20 mg daily, though no safe human dose is established.
- What are the risks of Cardarine (GW-501516)?
- Long-term rodent studies found it caused cancer across multiple organs Human safety and long-term effects remain essentially unknown Development was abandoned; not approved for human use and banned in sport
About SARMs
- What they are
- Selective androgen receptor modulators — oral compounds designed to hit muscle and bone androgen receptors while sparing prostate and skin. None is an approved medicine anywhere.
- How they're run
- Taken orally once a day, typically in 8–12 week blocks.
- What to watch
- The "non-suppressive" reputation is marketing: most suppress natural testosterone, and several are liver-toxic. Independent testing repeatedly finds products containing something other than the label. Bloodwork before and after is the minimum.
Full guide
Cardarine (GW-501516): A Tracking Guide for a PPAR-Delta Agonist
A candid, harm-reduction look at cardarine, its endurance and fat-oxidation effects, and the rodent carcinogenicity signal that ended its development.
Other sarms
Peptid AI is an educational and self-tracking tool — not a medical service, and not a vendor. Nothing here is medical advice, a prescription, or an endorsement. Doses reflect what is commonly reported in research literature; they are not recommendations. Many compounds listed are experimental, not approved for human use, and/or controlled substances that are illegal to possess without a prescription in many countries. Always consult a qualified physician before starting, changing, or stopping any protocol.