Tag
Longevity
16 posts tagged “Longevity”.
Rapamycin (Sirolimus): A Tracking Guide for an mTOR Inhibitor
An evidence-aware look at rapamycin, the headline off-label longevity drug, what the human data actually shows, and what to monitor on intermittent dosing.
Urolithin A: A Tracking Guide for a Mitophagy Activator
An evidence-aware look at urolithin A, a gut-derived metabolite with human muscle and endurance data, sold as a well-tolerated supplement.
Spermidine: A Tracking Guide for a Polyamine Autophagy Inducer
An evidence-aware look at spermidine, a dietary polyamine linked to autophagy and longevity signals, sold as a wheat-germ-derived supplement.
Fisetin: A Tracking Guide for a Flavonoid Senolytic
An evidence-aware look at fisetin, a plant flavonoid used in intermittent senolytic protocols, and why the human data is still mostly preliminary.
5-Amino-1MQ: A Tracking Guide for an NNMT Inhibitor
What 5-Amino-1MQ is, why it is studied as a metabolic compound, and how a self-experimenter can structure tracking around very limited human data.
NR (Nicotinamide Riboside): Tracking a NAD+ Precursor
What NR is, how it compares to NMN, and how to track realistic outcomes from a vitamin B3 derivative marketed for cellular aging.
Metformin: The Old Drug in the Longevity Conversation
A tracking guide for metformin that takes its prescription status and side effects seriously.
MOTS-c: A Mitochondrial Peptide With Real Biology and Modest Human Data
What MOTS-c does, what it might do in humans, and how to track it honestly.
Humanin: A Tracking Guide for an Early-Stage Mitochondrial Peptide
A small peptide encoded in mitochondrial DNA with intriguing but very early evidence.
NAD+ Direct: IV, Subcutaneous, and the Question of Whether You Need Any of It
A tracking guide for direct NAD+ supplementation that takes the cost and evidence seriously.
NADH: The Reduced Form, Oral Route, and What It Might Actually Help
A focused tracking guide for oral NADH supplementation in fatigue, cognition, and Parkinson disease contexts.
Pinealon: Tracking a Short Khavinson Peptide
What Pinealon is, where it sits in the Khavinson peptide family, and how to track its proposed cognitive and stress effects honestly.
SS-31 (Elamipretide): Tracking a Mitochondria-Targeting Tetrapeptide
A tracking guide for SS-31/elamipretide, the cardiolipin-binding peptide studied in mitochondrial disease and heart failure.
Vilon: A Tracking Guide for a Short Khavinson Dipeptide
What Vilon is, where the research comes from, realistic expectations, and how to track a course if you choose to run one.
NMN: A Precursor With Big Claims and Measurable Realities
A tracking guide for NMN supplementation focused on what is actually measurable in humans.
Epitalon: Tracking a Longevity-Focused Protocol
Epitalon protocols last days, not weeks, and effects accumulate across cycles. Here is what to track if you want personal data that compounds over years.